Clinical data for patients 2 months of age and older
- Of the 17 pediatric patients 2 months to <2 years of age in 3 open-label studies, 7 patients (41%) reported a total of 11 hyperammonemic crises.1
- Of the 26 pediatric patients 6 to 17 years of age in two 12-month studies of RAVICTI, 5 patients (19%) reported a total of 5 hyperammonemic crises.1
- Of 51 adult patients in a 12-month study of RAVICTI, 7 patients (14%) reported a total of 10 hyperammonemic crises.1
aSix uncontrolled, open-label studies were conducted to assess monthly ammonia control and hyperammonemic crises in patients with urea cycle disorders (UCDs): 17 pediatric patients 2 months to <2 years of age, with 6 patients completing 12 months of treatment; 26 pediatric patients 6 to 17 years of age over a 12-month period; and 51 adults over a 12-month period.1
RAVICTI: Effective, 24/7 ammonia control with easy dosing1
- Easy-to-administer oral liquid that is nearly tasteless and odorless1,2
- Approved to treat UCD subtypes except NAGS deficiency1
- No pill or powder preparation1,2
- Easy for patients to make the switch from sodium phenylbutyrate (NaPBA) without any gap in treatment1
- Taken with meals via oral dosing syringe1
- With a simple calculation, dosage can be converted from NaPBA to RAVICTI1
RAVICTI is contraindicated in patients with known hypersensitivity to phenylbutyrate.1
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References: 1. RAVICTI [package insert]. Lake Forest, IL: Horizon Pharma USA, Inc.; 2019. 2. Mosteller RD. N Engl J Med. 1987;317(17):1098. doi:10.1056/nejm198710223171717.